IGF-1 LR3 (Long R3 IGF-1) — Dosing, Cycles, Half-Life & Side Effects
IGF-1 LR3 (Long R3 IGF-1) is a growth-factor peptide with a half-life of 20-30 hours. Modified IGF-1 with extended half-life due to arginine substitution at position 3 and 13 amino acid extension. Does not bind to IGF binding proteins, remaining active longer and having more potent anabolic effects. This page is educational harm-reduction reference compiled from peer-reviewed literature — not medical advice, not an endorsement, not a recommendation to use. Consult a licensed clinician before any decision.
Quick Facts
| Class | Growth Factors |
|---|---|
| Half-life | 20-30 hours |
| Hepatotoxicity | None |
| Suppression | 0/10 |
Typical Dosing Ranges
Common dose range: 20-50mcg/day subcutaneous or intramuscular
Cycle length: 4-6 weeks (then break)
Dose ranges are compiled from published pharmacokinetic studies and community-reported usage. Where a value is community-reported rather than clinically studied, this page and its structured data flag it. Lower end of any range is always the safer starting point.
Stacking Considerations
- No structural stacking blockers. Standard harm-reduction rules apply: minimize total androgen load, minimize oral exposure, and monitor bloodwork.
PCT Requirements
- Never stack two SERMs. Extend a single SERM (tamoxifen OR enclomiphene/clomiphene) rather than combining.
- Use the cycle planner to generate a full protocol based on your complete stack, not this compound alone.
Side Effect Profile
- Potential hypoglycemia risk
- May promote cancer growth (theoretical)
- Not for use with pre-existing tumors
- Can cause organ growth with chronic use
- Expensive
Known Interactions
No compound-specific interactions are catalogued in the current matrix. This does not mean no risk exists — it means there is no curated pairwise entry. Browse the full interaction matrix to cross-reference manually.
Related compounds
Monitoring (Bloodwork & Vitals)
- Comprehensive metabolic panel (baseline, mid-cycle, post-cycle)
- Lipid panel (total cholesterol, HDL, LDL, triglycerides)
- CBC (hemoglobin, hematocrit — watch for erythrocytosis)
- Sex-hormone panel (Total T, Free T, Estradiol sensitive, SHBG, LH, FSH)
- Blood pressure (weekly self-check; flag systolic >140 or diastolic >90)
Baseline bloodwork is recommended before any cycle. Discontinue if liver enzymes exceed 3× upper limit of normal or if hematocrit exceeds 54%.
Frequently Asked Questions
What is the half-life of IGF-1 LR3 (Long R3 IGF-1)?
IGF-1 LR3 (Long R3 IGF-1) has a half-life of approximately 20-30 hours. This figure is used to determine injection frequency (for esters) and post-cycle clearance timing.
What is the typical dose range for IGF-1 LR3 (Long R3 IGF-1)?
Commonly reported ranges for IGF-1 LR3 (Long R3 IGF-1): 20-50mcg/day subcutaneous or intramuscular. Cycle length: 4-6 weeks (then break). These are compiled from published studies and community-reported usage — individual response varies and lower end is always preferred.
Does IGF-1 LR3 (Long R3 IGF-1) suppress natural testosterone?
IGF-1 LR3 (Long R3 IGF-1) causes minimal suppression of the HPTA axis (score 0/10). PCT may still be advisable depending on stack and duration.
What is IGF-1 LR3 (Long R3 IGF-1) typically used for?
IGF-1 LR3 (Long R3 IGF-1) is commonly used for: Muscle growth, Recovery enhancement, Body composition. Intended-use context does not imply safety — every use case carries the same underlying pharmacological risks.
Is IGF-1 LR3 (Long R3 IGF-1) legal?
IGF-1 LR3 (Long R3 IGF-1) is a controlled substance in many jurisdictions (typically Schedule III in the US when it is an anabolic androgenic steroid). StackItSmart does not provide sourcing information. Possession, import, and use without a prescription carry legal consequences that vary by country and state.
Citations
Disclaimer
StackItSmart is an independent harm-reduction reference. The content above is compiled from peer-reviewed literature and is not medical advice, not an endorsement, and not a recommendation to use IGF-1 LR3 (Long R3 IGF-1). Performance-enhancing compounds carry legal, endocrine, cardiovascular, and hepatic risks. Consult a licensed clinician before any decision. StackItSmart does not provide sourcing, procurement, or dosing prescriptions.