ACP-105 — Dosing, Cycles, Half-Life & Side Effects

ACP-105 is a selective androgen receptor modulator (SARM) with a half-life of 4-6 hours. Partial agonist SARM with mild effects for lean mass and minimal suppression, based on preclinical data. This page is educational harm-reduction reference compiled from peer-reviewed literature — not medical advice, not an endorsement, not a recommendation to use. Consult a licensed clinician before any decision.

Quick Facts

ClassSelective Androgen Receptor Modulator
Half-life4-6 hours
AromatizationNo
HepatotoxicityLow
Suppression3/10
17α-alkylatedNo

Typical Dosing Ranges

Common dose range: 5-10mg/day

Cycle length: 8-12 weeks

Dose ranges are compiled from published pharmacokinetic studies and community-reported usage. Where a value is community-reported rather than clinically studied, this page and its structured data flag it. Lower end of any range is always the safer starting point.

Stacking Considerations

  • No structural stacking blockers. Standard harm-reduction rules apply: minimize total androgen load, minimize oral exposure, and monitor bloodwork.

PCT Requirements

  • Never stack two SERMs. Extend a single SERM (tamoxifen OR enclomiphene/clomiphene) rather than combining.
  • Use the cycle planner to generate a full protocol based on your complete stack, not this compound alone.

Side Effect Profile

  • Limited human data
  • Mild effects
  • Short half-life
  • Expensive

Known Interactions

No compound-specific interactions are catalogued in the current matrix. This does not mean no risk exists — it means there is no curated pairwise entry.

Monitoring (Bloodwork & Vitals)

  • Comprehensive metabolic panel (baseline, mid-cycle, post-cycle)
  • Lipid panel (total cholesterol, HDL, LDL, triglycerides)
  • CBC (hemoglobin, hematocrit — watch for erythrocytosis)
  • Sex-hormone panel (Total T, Free T, Estradiol sensitive, SHBG, LH, FSH)
  • Blood pressure (weekly self-check; flag systolic >140 or diastolic >90)

Baseline bloodwork is recommended before any cycle. Discontinue if liver enzymes exceed 3× upper limit of normal or if hematocrit exceeds 54%.

Frequently Asked Questions

What is the half-life of ACP-105?

ACP-105 has a half-life of approximately 4-6 hours. This figure is used to determine injection frequency (for esters) and post-cycle clearance timing.

What is the typical dose range for ACP-105?

Commonly reported ranges for ACP-105: 5-10mg/day. Cycle length: 8-12 weeks. These are compiled from published studies and community-reported usage — individual response varies and lower end is always preferred.

Does ACP-105 suppress natural testosterone?

ACP-105 causes moderate suppression of the HPTA axis (score 3/10). PCT may still be advisable depending on stack and duration.

Is ACP-105 liver toxic?

Hepatotoxicity rating: Low. Non-17αα compound — liver stress is lower but still warrants periodic monitoring during a cycle.

Does ACP-105 aromatize to estrogen?

Aromatization profile: No. Minimal to no aromatization expected, so aromatase inhibitors are not typically indicated for this compound alone.

What is ACP-105 typically used for?

ACP-105 is commonly used for: First SARM cycle, Cutting, Women. Intended-use context does not imply safety — every use case carries the same underlying pharmacological risks.

Citations

  1. Rosen J, Miner JN. 2002. Endocrinology — SARM class discovery; ACP-105 has no published human data

Disclaimer

StackItSmart is an independent harm-reduction reference. The content above is compiled from peer-reviewed literature and is not medical advice, not an endorsement, and not a recommendation to use ACP-105. Performance-enhancing compounds carry legal, endocrine, cardiovascular, and hepatic risks. Consult a licensed clinician before any decision. StackItSmart does not provide sourcing, procurement, or dosing prescriptions.

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