AC-262,536 — Dosing, Cycles, Half-Life & Side Effects

AC-262,536 is a selective androgen receptor modulator (SARM) with a half-life of 24 hours. Mild SARM for lean gains and cutting. This page is educational harm-reduction reference compiled from peer-reviewed literature — not medical advice, not an endorsement, not a recommendation to use. Consult a licensed clinician before any decision.

Quick Facts

ClassSelective Androgen Receptor Modulator
Half-life24 hours
AromatizationNo
HepatotoxicityLow
Suppression3/10
17α-alkylatedNo

Typical Dosing Ranges

Common dose range: 10-20mg/day

Cycle length: 8-12 weeks

Dose ranges are compiled from published pharmacokinetic studies and community-reported usage. Where a value is community-reported rather than clinically studied, this page and its structured data flag it. Lower end of any range is always the safer starting point.

Stacking Considerations

  • No structural stacking blockers. Standard harm-reduction rules apply: minimize total androgen load, minimize oral exposure, and monitor bloodwork.

PCT Requirements

  • Never stack two SERMs. Extend a single SERM (tamoxifen OR enclomiphene/clomiphene) rather than combining.
  • Use the cycle planner to generate a full protocol based on your complete stack, not this compound alone.

Side Effect Profile

  • Mild suppression
  • Limited research
  • Expensive
  • Weak effects

Known Interactions

No compound-specific interactions are catalogued in the current matrix. This does not mean no risk exists — it means there is no curated pairwise entry.

Monitoring (Bloodwork & Vitals)

  • Comprehensive metabolic panel (baseline, mid-cycle, post-cycle)
  • Lipid panel (total cholesterol, HDL, LDL, triglycerides)
  • CBC (hemoglobin, hematocrit — watch for erythrocytosis)
  • Sex-hormone panel (Total T, Free T, Estradiol sensitive, SHBG, LH, FSH)
  • Blood pressure (weekly self-check; flag systolic >140 or diastolic >90)

Baseline bloodwork is recommended before any cycle. Discontinue if liver enzymes exceed 3× upper limit of normal or if hematocrit exceeds 54%.

Frequently Asked Questions

What is the half-life of AC-262,536?

AC-262,536 has a half-life of approximately 24 hours. This figure is used to determine injection frequency (for esters) and post-cycle clearance timing.

What is the typical dose range for AC-262,536?

Commonly reported ranges for AC-262,536: 10-20mg/day. Cycle length: 8-12 weeks. These are compiled from published studies and community-reported usage — individual response varies and lower end is always preferred.

Does AC-262,536 suppress natural testosterone?

AC-262,536 causes moderate suppression of the HPTA axis (score 3/10). PCT may still be advisable depending on stack and duration.

Is AC-262,536 liver toxic?

Hepatotoxicity rating: Low. Non-17αα compound — liver stress is lower but still warrants periodic monitoring during a cycle.

Does AC-262,536 aromatize to estrogen?

Aromatization profile: No. Minimal to no aromatization expected, so aromatase inhibitors are not typically indicated for this compound alone.

What is AC-262,536 typically used for?

AC-262,536 is commonly used for: Cutting, Lean gains, Beginner cycles. Intended-use context does not imply safety — every use case carries the same underlying pharmacological risks.

Citations

  1. Gao W et al.. 2005. J Clin Endocrinol Metab — SARM class characterization; AC-262,536 has only preclinical data
  2. Gao W, et al. Selective androgen receptor modulator treatment improves muscle mass and strength. J Clin Endocrinol Metab 2005

Disclaimer

StackItSmart is an independent harm-reduction reference. The content above is compiled from peer-reviewed literature and is not medical advice, not an endorsement, and not a recommendation to use AC-262,536. Performance-enhancing compounds carry legal, endocrine, cardiovascular, and hepatic risks. Consult a licensed clinician before any decision. StackItSmart does not provide sourcing, procurement, or dosing prescriptions.

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