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StackItSmart
Methodology

How this is built

Reducing harm depends on the information being trustworthy. Every number and claim here is researched from primary literature and independently verified, rather than carried over from forums or an older version of this site.

Research

How compounds are researched

Each of the 124 compounds was researched independently against the primary literature using PubMed. Pharmacokinetics, organ-system risks, monitoring, and dose ranges were gathered from peer-reviewed sources, and every clinical claim was checked so that its citation actually resolves and supports the statement attached to it.

Where the human evidence is thin — as it is for many peptides, SARMs, and research chemicals — we say so plainly and grade the evidence accordingly, rather than dressing up preclinical data as certainty. “No adequate human data” is an honest, useful finding.

Counts across the site (124 compounds, 1,268 citations) are derived from a single content source, so they can never disagree from one page to the next.

Grading

What the evidence grades mean

A

Human randomised controlled trial or meta-analysis of RCTs.

B

Human observational, cohort, or case-control study.

C

Human case reports or case series only.

D

Preclinical (animal / in-vitro) or purely mechanistic — no adequate human data.

Editorial & safety

The guardrails we hold to

No sourcing, ever.

We never provide vendors, suppliers, prices, or any guidance on obtaining these compounds. If a source discusses procurement, we don't surface it.

No optimisation.

We report clinical dose ranges as the literature states them, attached to their risks. We never recommend a “best” dose or stack, and never frame content as how to get bigger, leaner, or stronger.

Cite everything.

Every clinical claim is tied to a primary source — a peer-reviewed human study wherever one exists. Blogs, forums, and vendor pages are never citations.

Risk-forward framing.

We lead with the dangers and the monitoring. The goal we assume for the reader is safety and medical oversight, not maximal results.

Adults only.

The site is age-gated to 21+ and carries an educational-only, not-medical-advice disclaimer throughout.

Licensing

Using this content

StackItSmart is educational and is not affiliated with any manufacturer. Content is released under a Creative Commons Attribution 4.0 licence — you may reuse it with attribution. It remains educational information, not medical advice, and does not create a doctor–patient relationship.